File Name: ketogenic diet and epilepsy .zip
With the rising demand for ketogenic diet therapy in adult epilepsy, there is a need for research describing the real-life effectiveness, retention, and safety of relevant services. Of the first referrals, 42 31 females, 11 males; mean age The most common reasons for discontinuing MKD were side effects and diet restrictiveness.
Citation Information : Journal of Epileptology. Finding an effective epilepsy treatment has been a challenge in medicine for centuries. This gives an incentive to search for therapies other than pharmacotherapy, e. The present review paper aims to present the current state of knowledge regarding the effectiveness of the KD, its mechanism of action, indications, method of treatment and potential adverse effects. The review covers relevant most recent up to March papers using PubMed and Medline databases.
Jump to navigation. Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges from the brain. In most people, seizures can be controlled by one or more antiepileptic medicines. For people who continue to have seizures drug-resistant epilepsy a special diet, a ketogenic diet, may be considered. Ketogenic diets are high in fat and low in carbohydrate. This review looked at the effects of ketogenic diets on seizure control, learning and memory, and behaviour. We also investigated the side effects of the diet and the number of people who withdrew from studies, plus the reasons why.
Epilepsy and the Ketogenic Diet pp Cite as. However, fasting as a treatment for seizures was less recognized. Fasting is the only therapeutic measure against epilepsy recorded in the Hippocratic collection 1. In the fifth century BC, Hippocrates reported on a man who had been seized by epileptic convulsions after having anointed himself before the fire in a bath, in winter.
From the Section on Pediatrics, Mayo Clinic. During the last two and one-half years, the ketogenic, or high fat, diet has been given a trial in the treatment of epilepsy in childhood. Thirty-seven patients with essential or idiopathic epilepsy, whose parents were able to comprehend and carry out the diet intelligently at home, have been observed over periods of from four months to two and one-half years.
Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. DOI: The Ketogenic Diet KD is a modality of treatment used since the s as a treatment for intractable epilepsy. It has been proposed as a dietary treatment that would produce similar benefits to fasting, which is already recorded in the Hippocratic collection.
The Ketogenic Diet KD is a modality of treatment used since the s as a treatment for intractable epilepsy. It has been proposed as a dietary treatment that would produce similar benefits to fasting, which is already recorded in the Hippocratic collection. Evidence shows that KD and its variants are a good alternative for non-surgical pharmacoresistant patients with epilepsy of any age, taking into account that the type of diet should be designed individually and that less-restrictive and more-palatable diets are usually better options for adults and adolescents. Epilepsy is a disabling and common neurological disease, which can be controlled successfully in most patients with one or more antiepileptic drugs. Some of these patients are not surgery candidates, so it is necessary to search for alternative treatments for epilepsy such as palliative surgery, neuromodulation, and a ketogenic diet KD. The classic ketogenic diet CKD consists of a high-fat and low-protein and carbohydrate diet, with restricted calories and fluids. The diet mimics the fasting state, altering the metabolism to use fats as a primary fuel source; catabolism of fatty acids in the liver produces ketone bodies KB , which induces urinary ketosis Rho,
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